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pubmed-article:7563009pubmed:abstractTextLocalization of virion-associated protein x (Vpx) of SIVmac 251 was studied in lymph nodes and liver of six SIVmac-infected monkeys. Vpx was found associated with the network of follicular dendritic cells and macrophages in lymph nodes and/or livers from five out of six animals by immunohistochemistry. Although the humoral response to Vpx occurs in only 50% of the animals, the presence of Vpx in target cell or antibodies to Vpx in all the monkeys studied, suggests that Vpx may be necessary for viral replication in vivo.lld:pubmed
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pubmed-article:7563009pubmed:articleTitlePresence of virion protein x (Vpx) of simian immunodeficiency virus SIVmac 251 in target cells in vivo.lld:pubmed
pubmed-article:7563009pubmed:affiliationUnité INSERM 74, Institut de Virologie de la Faculté de Médecine, Université Louis Pasteur, Strasbourg, France.lld:pubmed
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