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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1995-10-27
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pubmed:abstractText |
Localization of virion-associated protein x (Vpx) of SIVmac 251 was studied in lymph nodes and liver of six SIVmac-infected monkeys. Vpx was found associated with the network of follicular dendritic cells and macrophages in lymph nodes and/or livers from five out of six animals by immunohistochemistry. Although the humoral response to Vpx occurs in only 50% of the animals, the presence of Vpx in target cell or antibodies to Vpx in all the monkeys studied, suggests that Vpx may be necessary for viral replication in vivo.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0047-2565
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
35-42
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:7563009-Animals,
pubmed-meshheading:7563009-Antibodies, Viral,
pubmed-meshheading:7563009-Female,
pubmed-meshheading:7563009-Immunohistochemistry,
pubmed-meshheading:7563009-Kupffer Cells,
pubmed-meshheading:7563009-Liver,
pubmed-meshheading:7563009-Lymph Nodes,
pubmed-meshheading:7563009-Macaca mulatta,
pubmed-meshheading:7563009-Macrophages,
pubmed-meshheading:7563009-Male,
pubmed-meshheading:7563009-Simian Acquired Immunodeficiency Syndrome,
pubmed-meshheading:7563009-Simian immunodeficiency virus,
pubmed-meshheading:7563009-Time Factors,
pubmed-meshheading:7563009-Viral Regulatory and Accessory Proteins,
pubmed-meshheading:7563009-Virus Replication
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pubmed:year |
1995
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pubmed:articleTitle |
Presence of virion protein x (Vpx) of simian immunodeficiency virus SIVmac 251 in target cells in vivo.
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pubmed:affiliation |
Unité INSERM 74, Institut de Virologie de la Faculté de Médecine, Université Louis Pasteur, Strasbourg, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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