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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1995-11-3
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pubmed:abstractText |
The human granulocytotropic ehrlichia and Ehrlichia equi produce similar diseases in their respective host species (humans, horses). Currently, the phylogenetic and biologic relationships of these 2 uncultured pathogens remain unclear. Previous studies have revealed nucleotide sequence similarity approaching identity at the level of the 16S ribosomal RNA gene. To investigate the biologic similarities of these 2 ehrlichiae, the susceptibility of horses to the human agent was tested by intravenous inoculation of infected human blood. The results demonstrate that the human granulocytotropic ehrlichia produces a disease in the horse indistinguishable from that caused by E. equi, providing biologic evidence that these 2 organisms are highly related and potentially conspecific. It is possible that cases of human illness now attributed to human granulocytotropic ehrlichia may in fact be caused by 1 or more strains of an ehrlichia known chiefly as an equine pathogen.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
|
pubmed:issn |
0022-1899
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
172
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1141-4
|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7561199-Aged,
pubmed-meshheading:7561199-Animals,
pubmed-meshheading:7561199-Base Sequence,
pubmed-meshheading:7561199-Blood Cell Count,
pubmed-meshheading:7561199-DNA, Ribosomal,
pubmed-meshheading:7561199-Ehrlichia,
pubmed-meshheading:7561199-Ehrlichiosis,
pubmed-meshheading:7561199-Female,
pubmed-meshheading:7561199-Fever,
pubmed-meshheading:7561199-Granulocytes,
pubmed-meshheading:7561199-Horse Diseases,
pubmed-meshheading:7561199-Horses,
pubmed-meshheading:7561199-Humans,
pubmed-meshheading:7561199-Male,
pubmed-meshheading:7561199-Molecular Sequence Data,
pubmed-meshheading:7561199-Neutrophils,
pubmed-meshheading:7561199-RNA, Ribosomal, 16S
|
pubmed:year |
1995
|
pubmed:articleTitle |
Transmission and passage in horses of the agent of human granulocytic ehrlichiosis.
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pubmed:affiliation |
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis 95616-8737, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Case Reports,
Research Support, Non-U.S. Gov't
|