| pubmed-article:7552860 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7552860 | lifeskim:mentions | umls-concept:C0034656 | lld:lifeskim |
| pubmed-article:7552860 | lifeskim:mentions | umls-concept:C0150097 | lld:lifeskim |
| pubmed-article:7552860 | lifeskim:mentions | umls-concept:C0030899 | lld:lifeskim |
| pubmed-article:7552860 | lifeskim:mentions | umls-concept:C1568868 | lld:lifeskim |
| pubmed-article:7552860 | lifeskim:mentions | umls-concept:C1708528 | lld:lifeskim |
| pubmed-article:7552860 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:7552860 | pubmed:dateCreated | 1995-10-26 | lld:pubmed |
| pubmed-article:7552860 | pubmed:abstractText | Oral mucositis is a frequent side effect of cancer therapy. No effective method of prophylaxis is currently available. We conducted a randomized, double-blind, placebo-controlled, crossover trial of pentoxifylline to evaluate its potential in preventing mucositis in cancer patients receiving chemotherapy. Ten cancer patients were randomized for treatment with a 15-day course of 400 mg of pentoxifylline given orally four times daily. Concurrent chemotherapy consisted of bolus cisplatin and infusional 5-fluorouracil. Mucositis was evaluated with the use of the Oral Assessment Guide developed at the University of Nebraska. Patients completing two cycles of chemotherapy--one with pentoxifylline and one with placebo--were evaluated for prophylaxis efficacy. Comparison of the oral assessment scores of the two cycles with a two-sided Student's t test failed to demonstrate a cytoprotective effect for pentoxifylline over placebo. We conclude that pentoxifylline as given in this study is ineffective for preventing mucositis in patients receiving cisplatin and 5-FU. | lld:pubmed |
| pubmed-article:7552860 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7552860 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7552860 | pubmed:citationSubset | D | lld:pubmed |
| pubmed-article:7552860 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7552860 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7552860 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7552860 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7552860 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7552860 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:7552860 | pubmed:issn | 1079-2104 | lld:pubmed |
| pubmed-article:7552860 | pubmed:author | pubmed-author:VaughnBB | lld:pubmed |
| pubmed-article:7552860 | pubmed:author | pubmed-author:GarewalH SHS | lld:pubmed |
| pubmed-article:7552860 | pubmed:author | pubmed-author:VerdiC JCJ | lld:pubmed |
| pubmed-article:7552860 | pubmed:author | pubmed-author:KoenigL MLM | lld:pubmed |
| pubmed-article:7552860 | pubmed:author | pubmed-author:BurkheadTT | lld:pubmed |
| pubmed-article:7552860 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7552860 | pubmed:volume | 80 | lld:pubmed |
| pubmed-article:7552860 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7552860 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7552860 | pubmed:pagination | 36-42 | lld:pubmed |
| pubmed-article:7552860 | pubmed:dateRevised | 2006-4-24 | lld:pubmed |
| pubmed-article:7552860 | pubmed:meshHeading | pubmed-meshheading:7552860-... | lld:pubmed |
| pubmed-article:7552860 | pubmed:meshHeading | pubmed-meshheading:7552860-... | lld:pubmed |
| pubmed-article:7552860 | pubmed:meshHeading | pubmed-meshheading:7552860-... | lld:pubmed |
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| pubmed-article:7552860 | pubmed:meshHeading | pubmed-meshheading:7552860-... | lld:pubmed |
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| pubmed-article:7552860 | pubmed:meshHeading | pubmed-meshheading:7552860-... | lld:pubmed |
| pubmed-article:7552860 | pubmed:meshHeading | pubmed-meshheading:7552860-... | lld:pubmed |
| pubmed-article:7552860 | pubmed:meshHeading | pubmed-meshheading:7552860-... | lld:pubmed |
| pubmed-article:7552860 | pubmed:meshHeading | pubmed-meshheading:7552860-... | lld:pubmed |
| pubmed-article:7552860 | pubmed:meshHeading | pubmed-meshheading:7552860-... | lld:pubmed |
| pubmed-article:7552860 | pubmed:meshHeading | pubmed-meshheading:7552860-... | lld:pubmed |
| pubmed-article:7552860 | pubmed:meshHeading | pubmed-meshheading:7552860-... | lld:pubmed |
| pubmed-article:7552860 | pubmed:meshHeading | pubmed-meshheading:7552860-... | lld:pubmed |
| pubmed-article:7552860 | pubmed:meshHeading | pubmed-meshheading:7552860-... | lld:pubmed |
| pubmed-article:7552860 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:7552860 | pubmed:articleTitle | A double-blind, randomized, placebo-controlled, crossover trial of pentoxifylline for the prevention of chemotherapy-induced oral mucositis. | lld:pubmed |
| pubmed-article:7552860 | pubmed:affiliation | Section of Hematology/Oncology, Tucson Veteran's Affairs Medical Center, Ariz., USA. | lld:pubmed |
| pubmed-article:7552860 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7552860 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:7552860 | pubmed:publicationType | Randomized Controlled Trial | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7552860 | lld:pubmed |
