Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1995-9-1
pubmed:abstractText
Chlorpyrifos (CPF) is a broad-spectrum organophosphate insecticide used to control mosquitos and household insects. In man it has toxic effects on the central nervous system, the cardiovascular system and the respiratory system. This study investigated the toxicity of CPF on nervous system development using the midbrain micromass culture system. Chlorpyrifos was tested as a marketed formulation and in 3 solvents. All demonstrated toxicity in midbrain micromass cells with IC50 values below 30 ug/mL, indicating a potent teratogen.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0145-6296
pubmed:author
pubmed:issnType
Print
pubmed:volume
37
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
118-21
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Effects of chlorpyrifos on neuronal development in rat embryo midbrain micromass cultures.
pubmed:affiliation
Department of Pharmaceutical Sciences, College of Pharmacy and Allied Health Professions, St John's University, Jamaica, NY 11439, USA.
pubmed:publicationType
Journal Article