Switch to
Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5 Pt 2
|
pubmed:dateCreated |
1995-6-19
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pubmed:abstractText |
To study the long-term safety and effectiveness of ipratropium bromide nasal spray 0.03% in the treatment of nonallergic perennial rhinitis, we administered this medication for 1 year in an open-label trial involving 285 patients. Our intention was to maintain the highest protocol dose possible to gain a clearer picture of the long-term side effect profile of the compound. Ipratropium bromide was well tolerated with no serious side effects in this patient population. It provided a significant improvement in rhinorrhea throughout the year-long trial; only 17 of 285 patients (6%) were considered treatment failures. There was an improvement in patient quality of life, as well as a substantial reduction in the need for other medications (antihistamines, decongestants, and nasal steroids) used to treat perennial rhinitis symptoms.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0091-6749
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
95
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pubmed:owner |
NLM
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pubmed:authorsComplete |
N
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pubmed:pagination |
1123-7
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:7538520-Adult,
pubmed-meshheading:7538520-Aged,
pubmed-meshheading:7538520-Drug Therapy, Combination,
pubmed-meshheading:7538520-Drug Tolerance,
pubmed-meshheading:7538520-Female,
pubmed-meshheading:7538520-Glucocorticoids,
pubmed-meshheading:7538520-Histamine H1 Antagonists,
pubmed-meshheading:7538520-Humans,
pubmed-meshheading:7538520-Ipratropium,
pubmed-meshheading:7538520-Longitudinal Studies,
pubmed-meshheading:7538520-Male,
pubmed-meshheading:7538520-Middle Aged,
pubmed-meshheading:7538520-Nasal Decongestants,
pubmed-meshheading:7538520-Nasal Mucosa,
pubmed-meshheading:7538520-Nebulizers and Vaporizers,
pubmed-meshheading:7538520-Rhinitis, Allergic, Perennial
|
pubmed:year |
1995
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pubmed:articleTitle |
Use of ipratropium bromide nasal spray in chronic treatment of nonallergic perennial rhinitis, alone and in combination with other perennial rhinitis medications.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Controlled Clinical Trial
|