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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1995-3-1
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pubmed:abstractText |
Hepatobiliary disease is the second most common cause of mortality in patients with cystic fibrosis (CF). In the liver, only the intrahepatic biliary epithelial (IBE) cells express cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel. The aim of this study was to determine whether human CF-derived IBE cells can be infected with adenovirus and the CF phenotype complemented.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0016-5085
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
108
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pubmed:owner |
NLM
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pubmed:authorsComplete |
N
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pubmed:pagination |
584-92
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:7530672-3T3 Cells,
pubmed-meshheading:7530672-Animals,
pubmed-meshheading:7530672-Bile Ducts,
pubmed-meshheading:7530672-Cell Line,
pubmed-meshheading:7530672-Cystic Fibrosis,
pubmed-meshheading:7530672-Cystic Fibrosis Transmembrane Conductance Regulator,
pubmed-meshheading:7530672-Epithelium,
pubmed-meshheading:7530672-Gene Therapy,
pubmed-meshheading:7530672-Genetic Complementation Test,
pubmed-meshheading:7530672-Genetic Vectors,
pubmed-meshheading:7530672-Humans,
pubmed-meshheading:7530672-Membrane Proteins,
pubmed-meshheading:7530672-Mice,
pubmed-meshheading:7530672-Transfection
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pubmed:year |
1995
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pubmed:articleTitle |
Correction of the cystic fibrosis defect by gene complementation in human intrahepatic biliary epithelial cell lines.
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pubmed:affiliation |
Department of Pediatrics, New England Medical Center, Boston, Massachusetts.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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