Linked Life Data

7528317

Source:http://linkedlifedata.com/resource/pubmed/id/7528317

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
1995-1-26
pubmed:abstractText
The purpose of this symposium was to evaluate the hypothesis that the beneficial effects of training are the result of training-induced adaptations in the coronary circulation. The approach is to review, summarize, and evaluate data concerning the effects of exercise training on the coronary circulation. Results indicate that aerobic exercise training induces an increase in both blood flow capacity and capillary exchange capacity. These functional changes are the result of two major types of adaptive responses: structural vascular adaptation and altered control of vascular resistance. Structural vascular adaptation occurs in response to exercise training in at least two forms: increases in the cross-sectional area of the proximal coronary arteries, and angiogenesis. Training-induced changes in coronary vascular control have been shown to include altered responses of the coronary circulation and isolated coronary arteries to vasoactive substances, changes in endothelium-mediated vasoregulation, and alterations in the cellular-molecular control of intracellular free Ca2+ in both endothelial and vascular smooth muscle cells isolated from coronary arteries of exercise trained animals. The potential impact of these training-induced adaptations on the coronary collateral circulation and atherosclerotic coronary disease are discussed.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0195-9131
pubmed:author
pubmed:issnType
Print
pubmed:volume
26
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1226-9
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Effects of exercise training on coronary circulation: introduction.
pubmed:affiliation
Department of Veterinary Biomedical Sciences, University of Missouri, Columbia 65211.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.