Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1995-1-12
pubmed:abstractText
The objectives of this phase I trial were to determine the dose-limiting toxicities (DLTs) of the novel topoisomerase I inhibitor topotecan combined with cisplatin, to define the maximum-tolerated doses (MTDs) of the combination without and with the use of filgrastim, and to define recommended doses for phase II trials.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0732-183X
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2743-50
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed-meshheading:7527456-Adult, pubmed-meshheading:7527456-Aged, pubmed-meshheading:7527456-Antineoplastic Combined Chemotherapy Protocols, pubmed-meshheading:7527456-Breast Neoplasms, pubmed-meshheading:7527456-Camptothecin, pubmed-meshheading:7527456-Carcinoma, Non-Small-Cell Lung, pubmed-meshheading:7527456-Cisplatin, pubmed-meshheading:7527456-Colorectal Neoplasms, pubmed-meshheading:7527456-Dose-Response Relationship, Drug, pubmed-meshheading:7527456-Female, pubmed-meshheading:7527456-Granulocyte Colony-Stimulating Factor, pubmed-meshheading:7527456-Humans, pubmed-meshheading:7527456-Kidney Neoplasms, pubmed-meshheading:7527456-Lung Neoplasms, pubmed-meshheading:7527456-Male, pubmed-meshheading:7527456-Middle Aged, pubmed-meshheading:7527456-Neoplasms, pubmed-meshheading:7527456-Neoplasms, Unknown Primary, pubmed-meshheading:7527456-Neutropenia, pubmed-meshheading:7527456-Recombinant Proteins, pubmed-meshheading:7527456-Salivary Gland Neoplasms, pubmed-meshheading:7527456-Stomach Neoplasms, pubmed-meshheading:7527456-Topotecan
pubmed:year
1994
pubmed:articleTitle
Phase I study of topotecan and cisplatin in patients with advanced solid tumors: a cancer and leukemia group B study.
pubmed:affiliation
University of Tennessee, Memphis 38163.
pubmed:publicationType
Journal Article, Clinical Trial, Research Support, U.S. Gov't, P.H.S., Clinical Trial, Phase I