Linked Life Data

7526227

Source:http://linkedlifedata.com/resource/pubmed/id/7526227

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1994-11-28
pubmed:abstractText
The effects of pretreatment with interleukin-1 (IL-1) on neurite growth and cell survival of rat superior cervical ganglion (SCG) explants were examined. Neonate rat SCG explants were cultured with serum-containing growth media. Pretreatment with IL-1 beta (30 U/ml) for 3 hours stimulated neurite outgrowth of the SCG explant, which was inhibited by the addition of anti-nerve growth factor (NGF) antibody to the growth medium. Adult rat autologous SCG with the same pretreatment and non-treated ganglia were transplanted into the lateral ventricle. Histological evaluation of the grafts 2 weeks after transplantation revealed that the pretreated SCG cells survived better. Pretreatment with IL-1 may achieve the NGF-mediated neurotrophic effect in sympathetic ganglionic neurons resulting in enhanced graft survival.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0470-8105
pubmed:author
pubmed:issnType
Print
pubmed:volume
34
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
407-11
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Pretreatment with interleukin-1 enhances survival of sympathetic ganglionic neuron grafts.
pubmed:affiliation
Department of Neurological Surgery, Wakayama Medical College.
pubmed:publicationType
Journal Article, In Vitro