pubmed-article:7518757 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:7518757 | lifeskim:mentions | umls-concept:C0034709 | lld:lifeskim |
pubmed-article:7518757 | lifeskim:mentions | umls-concept:C1704256 | lld:lifeskim |
pubmed-article:7518757 | lifeskim:mentions | umls-concept:C0026844 | lld:lifeskim |
pubmed-article:7518757 | lifeskim:mentions | umls-concept:C1135918 | lld:lifeskim |
pubmed-article:7518757 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
pubmed-article:7518757 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
pubmed-article:7518757 | lifeskim:mentions | umls-concept:C1515406 | lld:lifeskim |
pubmed-article:7518757 | lifeskim:mentions | umls-concept:C1323362 | lld:lifeskim |
pubmed-article:7518757 | pubmed:issue | 2 | lld:pubmed |
pubmed-article:7518757 | pubmed:dateCreated | 1994-8-22 | lld:pubmed |
pubmed-article:7518757 | pubmed:abstractText | 1. This study examined the effects of transforming growth factor-beta 1 (TGF-beta 1) on platelet-derived growth factor-BB (PDGF-BB)-stimulated DNA synthesis, [125I]-PDGF-BB receptor binding and PDGF-beta receptor mRNA expression in vascular smooth muscle cells (VSMC) isolated from Wistar-Kyoto (WKY) rats and spontaneously hypertensive rats (SHR). 2. TGF-beta 1 inhibited by 40% DNA synthesis stimulated by PDGF-BB in VSMC from WKY rats but potentiated by 20% growth factor-stimulated DNA synthesis in VSMC from the SHR. 3. Since the difference in effect of TGF-beta 1 could not be attributed to differential regulation of [125I]-PDGF-BB binding activity and PDGF-beta receptor mRNA expression, it is suggested that alterations in intracellular signalling pathways may account for the differential effects of TGF-beta 1 on PDGF-BB-stimulated DNA synthesis in VSMC from SHR and WKY rats. | lld:pubmed |
pubmed-article:7518757 | pubmed:language | eng | lld:pubmed |
pubmed-article:7518757 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7518757 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:7518757 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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pubmed-article:7518757 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7518757 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7518757 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7518757 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7518757 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7518757 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7518757 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:7518757 | pubmed:month | Feb | lld:pubmed |
pubmed-article:7518757 | pubmed:issn | 0305-1870 | lld:pubmed |
pubmed-article:7518757 | pubmed:author | pubmed-author:BobikAA | lld:pubmed |
pubmed-article:7518757 | pubmed:author | pubmed-author:SaltisJJ | lld:pubmed |
pubmed-article:7518757 | pubmed:author | pubmed-author:AgrotisAA | lld:pubmed |
pubmed-article:7518757 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:7518757 | pubmed:volume | 21 | lld:pubmed |
pubmed-article:7518757 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:7518757 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:7518757 | pubmed:pagination | 145-8 | lld:pubmed |
pubmed-article:7518757 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
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pubmed-article:7518757 | pubmed:year | 1994 | lld:pubmed |
pubmed-article:7518757 | pubmed:articleTitle | Effect of transforming growth factor-beta 1 on platelet-derived growth factor receptor binding and gene expression in vascular smooth muscle cells from SHR and WKY rats. | lld:pubmed |
pubmed-article:7518757 | pubmed:affiliation | Baker Medical Research Institute, Alfred Hospital, Prahran, Victoria, Australia. | lld:pubmed |
pubmed-article:7518757 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:7518757 | pubmed:publicationType | Comparative Study | lld:pubmed |
pubmed-article:7518757 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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