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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
1994-8-4
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pubmed:abstractText |
An undifferentiated deeply invasive ureteral carcinoma with syncytiotrophoblastic differentiation was analyzed for the synthesis of human chorionic gonadotropin beta-subunit by immunohistochemistry and Northern blot analysis. Human chorionic gonadotropin beta-subunit was localized immunohistochemically to syncytiotrophoblastic cells and scattered mononuclear tumor cells. Human chorionic gonadotropin beta-subunit gene was expressed at a high level by Northern blot analysis. To our knowledge, this is the first report demonstrating the synthesis of human chorionic gonadotropin beta-subunit at the transcriptional level in a urothelial carcinoma.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0003-9985
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
118
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
715-7
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:7517658-Aged,
pubmed-meshheading:7517658-Aged, 80 and over,
pubmed-meshheading:7517658-Base Sequence,
pubmed-meshheading:7517658-Blotting, Northern,
pubmed-meshheading:7517658-Carcinoma, Transitional Cell,
pubmed-meshheading:7517658-Cell Differentiation,
pubmed-meshheading:7517658-Chorionic Gonadotropin,
pubmed-meshheading:7517658-Chorionic Gonadotropin, beta Subunit, Human,
pubmed-meshheading:7517658-DNA, Complementary,
pubmed-meshheading:7517658-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:7517658-Humans,
pubmed-meshheading:7517658-Immunohistochemistry,
pubmed-meshheading:7517658-Male,
pubmed-meshheading:7517658-Middle Aged,
pubmed-meshheading:7517658-Molecular Sequence Data,
pubmed-meshheading:7517658-Peptide Fragments,
pubmed-meshheading:7517658-RNA, Neoplasm,
pubmed-meshheading:7517658-Trophoblasts,
pubmed-meshheading:7517658-Ureteral Neoplasms,
pubmed-meshheading:7517658-Urinary Bladder Neoplasms
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pubmed:year |
1994
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pubmed:articleTitle |
Human chorionic gonadotropin beta-subunit synthesis by undifferentiated urothelial carcinoma with syncytiotrophoblastic differentiation.
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pubmed:affiliation |
Department of Pathology, Northwestern University Medical School, Chicago, Ill 60611-3008.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Case Reports
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