Linked Life Data

7517466

Source:http://linkedlifedata.com/resource/pubmed/id/7517466

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1994-8-2
pubmed:abstractText
In guinea pig ileal circular muscle, electrical stimulations by a train of 10-100 pulses (0.05-msec duration, 10 Hz) produced tetrodotoxin-sensitive "off" contractions that were initiated upon the termination of stimulations. Atropine at 10(-6) M did not inhibit the "off" contractions. FK224 at 10(-5) M, a dual antagonist for NK1- and NK2-receptors, but not 10(-7) M CP-96,345, an antagonist for NK1-receptors, almost abolished the "off" contractions in the presence of atropine. These results suggest that the neurogenic "off" contraction was mediated mainly by NK2-receptors in the circular muscle of guinea pig ileum.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0021-5198
pubmed:author
pubmed:issnType
Print
pubmed:volume
64
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
213-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Neurogenic "off" contractions are mediated by NK2-receptors in the circular muscle of guinea pig ileum.
pubmed:affiliation
Department of Pharmacology, Faculty of Pharmaceutical Sciences, Kanazawa University, Japan.
pubmed:publicationType
Journal Article, In Vitro