Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1994-6-16
pubmed:abstractText
The risk of Down's syndrome pregnancies can be estimated by quantitation of maternal serum markers, namely alpha-fetoprotein, unconjugated estriol and human chorionic gonadotropin (triple test). A prospective study of 2892 pregnant women (median age 33.5 years) is reported. The detection rate of Down's syndrome pregnancies was 80% (confidence intervals 45%-100%) when a risk of 1:380 or greater was considered "screen positive", the false positive rate was 13.3% (confidence intervals 12.0%-14.5%). The importance of the accurate assessment of gestational age and the time of blood sampling are emphasized. Our findings are compared with similar studies performed in other laboratories.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0940-5437
pubmed:author
pubmed:issnType
Print
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
N
pubmed:pagination
49-53
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:7514056-Adult, pubmed-meshheading:7514056-Amniocentesis, pubmed-meshheading:7514056-Biological Markers, pubmed-meshheading:7514056-Chorionic Gonadotropin, pubmed-meshheading:7514056-Cohort Studies, pubmed-meshheading:7514056-Down Syndrome, pubmed-meshheading:7514056-Estriol, pubmed-meshheading:7514056-False Positive Reactions, pubmed-meshheading:7514056-Female, pubmed-meshheading:7514056-Gestational Age, pubmed-meshheading:7514056-Humans, pubmed-meshheading:7514056-Karyotyping, pubmed-meshheading:7514056-Mass Screening, pubmed-meshheading:7514056-Maternal Age, pubmed-meshheading:7514056-Pregnancy, pubmed-meshheading:7514056-Pregnancy, High-Risk, pubmed-meshheading:7514056-Prenatal Diagnosis, pubmed-meshheading:7514056-Prospective Studies, pubmed-meshheading:7514056-Risk, pubmed-meshheading:7514056-alpha-Fetoproteins
pubmed:year
1994
pubmed:articleTitle
Maternal serum markers. Estimation of the risk of Down's syndrome: a prospective study.
pubmed:affiliation
Ente Ospedaliero Sant'Anna, USL-IX, Turin, Italy.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't