Linked Life Data

7510024

Source:http://linkedlifedata.com/resource/pubmed/id/7510024

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1994-4-7
pubmed:abstractText
Cytogenetic studies revealed a significant increase in the frequency of structural chromosome aberrations of peritoneal macrophages from hyperimmune Swiss mice after ovariectomy. The administration of the nitroarene benznidazole caused a large number of chromosomal deletions in peritoneal macrophages of sham-ovariectomized animals. The clastogenic effect of benznidazole was much greater in peritoneal macrophages of ovariectomized mice. The anti-oxidant alpha-tocopherol protected the peritoneal macrophages from developing ovariectomy- or benznidazole-induced chromosomal aberrations, thus suggesting free radical damage in these processes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0027-5107
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
305
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
145-50
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
The anticlastogenic effect of tocopherol in peritoneal macrophages of benznidazole-treated and ovariectomized mice.
pubmed:affiliation
Department of Genetics and Morphology, University of Brasilia, DF, Brazil.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't