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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
1994-1-25
|
| pubmed:abstractText |
By combining immunoprecipitation of BoLA molecules with monoclonal antibodies raised against 2 different major histocompatibility class II antigens, TH14B and TH81A, and western blotting using the anti-HLA DR alpha monoclonal antibody DA6-147, we characterized an epitope conserved on BoLA- and HLA-DR alpha chains. This epitope, not accessible on intact cells, was revealed after cell lysis. In addition, these results allowed us to define TH14B as an anti-BoLA-DR monoclonal antibody whereas TH81A, raised against the products of a second MHC locus, is probably an anti-BoLA-DQ monoclonal antibody.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0928-4249
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
24
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
402-7
|
| pubmed:dateRevised |
2007-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:7505154-Animals,
pubmed-meshheading:7505154-Antibodies, Monoclonal,
pubmed-meshheading:7505154-Blotting, Western,
pubmed-meshheading:7505154-Cattle,
pubmed-meshheading:7505154-Cattle Diseases,
pubmed-meshheading:7505154-Epitopes,
pubmed-meshheading:7505154-HLA-DR Antigens,
pubmed-meshheading:7505154-Histocompatibility Antigens Class II,
pubmed-meshheading:7505154-Lymphoma, Non-Hodgkin,
pubmed-meshheading:7505154-Precipitin Tests,
pubmed-meshheading:7505154-Tumor Cells, Cultured
|
| pubmed:year |
1993
|
| pubmed:articleTitle |
The DA6-147 monoclonal antibody raised against the HLA-DR alpha chain identifies a cryptic epitope on the BoLA-DR alpha chain.
|
| pubmed:affiliation |
URA-INRA, Immunopathologie Cellulaire et Moléculaire, Ecole Nationale Vétérinaire, Alfort, France.
|
| pubmed:publicationType |
Journal Article
|