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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1996-1-16
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pubmed:abstractText |
Serum samples from 1,221 Ecuadorian children 0 to 5 years of age and from 236 German subjects were tested by enzyme-linked immunosorbent assay for class-specific antibodies to the capsular polysaccharide of Haemophilus influenzae type b (PRP antigen). A gradual prevalence increase of and mean titer increase in immunoglobulin M (IgM) antibody was seen in Ecuadorian but not in German children older than 6 months. At the end of the first year of life, about 50% of the Ecuadorian children showed IgM and IgG antibody to PRP. Seroepidemiological analysis revealed that living at a low altitude and lower calorie intake (a proxy measure of breast-feeding) were factors associated with earlier acquisition of PRP antibody. Children from low-altitude areas of Ecuador also experienced significantly more episodes of significant respiratory infections. The acquisition of PRP-reactive antibodies in Ecuadorian children might thus reflect exposure to encapsulated H. influenzae type b in lower respiratory tract infections.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496916-1083399,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496916-1431250,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496916-1452644,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496916-1624581,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496916-1862276,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496916-2167333,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496916-2205656,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496916-408432,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496916-48191,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496916-6602191,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496916-6607287,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7496916-6783703
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1071-412X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
21-5
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:7496916-Antibodies, Bacterial,
pubmed-meshheading:7496916-Child, Preschool,
pubmed-meshheading:7496916-Ecuador,
pubmed-meshheading:7496916-Female,
pubmed-meshheading:7496916-Germany,
pubmed-meshheading:7496916-Haemophilus Infections,
pubmed-meshheading:7496916-Haemophilus influenzae,
pubmed-meshheading:7496916-Humans,
pubmed-meshheading:7496916-Immunoglobulin G,
pubmed-meshheading:7496916-Immunoglobulin M,
pubmed-meshheading:7496916-Infant,
pubmed-meshheading:7496916-Infant, Newborn,
pubmed-meshheading:7496916-Male,
pubmed-meshheading:7496916-Polysaccharides,
pubmed-meshheading:7496916-Polysaccharides, Bacterial
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pubmed:year |
1994
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pubmed:articleTitle |
Antibody response to polyribosyl-ribitol phosphate antigen of Haemophilus influenzae in Ecuadorian and German children.
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pubmed:affiliation |
Nestlé Research Centre, Nestec Ltd., Lausanne, Switzerland.
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pubmed:publicationType |
Journal Article
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