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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4 Pt 1
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pubmed:dateCreated |
1995-12-12
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pubmed:abstractText |
The effects of lipid administration on carbohydrate oxidation rate remain controversial, particularly in critically ill patients. The aim of this study was to determine the effects of these patients of a continuous lipid infusion on glucose metabolism using indirect calorimetry and stable isotopes. We studied seven patients, mechanically ventilated, during two consecutive 24-h periods. Throughout the first period they received a continuous infusion of glucose (2 mg.kg-1.min-1) and amino acids. During the second period, in addition to the glucose, they received a continuous infusion of 1 mg.kg-1.min-1 of long-chain triglycerides emulsion. Substrate oxidation rates were calculated from pulmonary gas exchange and nitrogen excretion measurements. Glucose kinetic parameters were measured using primed constant infusions of [6,6-2H2]glucose and [1-13C]glucose. The lipid infusion did not modify the glucose metabolism parameters; 45% of the lipid supply was stored.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0002-9513
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
269
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
E753-8
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:7485491-Aged,
pubmed-meshheading:7485491-Calorimetry, Indirect,
pubmed-meshheading:7485491-Carbon Dioxide,
pubmed-meshheading:7485491-Critical Illness,
pubmed-meshheading:7485491-Female,
pubmed-meshheading:7485491-Glucose,
pubmed-meshheading:7485491-Humans,
pubmed-meshheading:7485491-Infusions, Intravenous,
pubmed-meshheading:7485491-Lipids,
pubmed-meshheading:7485491-Male,
pubmed-meshheading:7485491-Middle Aged,
pubmed-meshheading:7485491-Oxygen Consumption,
pubmed-meshheading:7485491-Parenteral Nutrition,
pubmed-meshheading:7485491-Respiration
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pubmed:year |
1995
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pubmed:articleTitle |
Effects of a continuous lipid infusion on glucose metabolism in critically ill patients.
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pubmed:affiliation |
Service d'Anesthésie-Réanimation, Hôpital Edouard Herriot, Lyon, France.
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pubmed:publicationType |
Journal Article,
Clinical Trial
|