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| pubmed-article:7478990 | lifeskim:mentions | umls-concept:C0521447 | lld:lifeskim |
| pubmed-article:7478990 | lifeskim:mentions | umls-concept:C0073423 | lld:lifeskim |
| pubmed-article:7478990 | lifeskim:mentions | umls-concept:C1417606 | lld:lifeskim |
| pubmed-article:7478990 | lifeskim:mentions | umls-concept:C1521761 | lld:lifeskim |
| pubmed-article:7478990 | pubmed:issue | 18 | lld:pubmed |
| pubmed-article:7478990 | pubmed:dateCreated | 1995-11-24 | lld:pubmed |
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| pubmed-article:7478990 | pubmed:abstractText | It has been shown that the monomethylated cap structure plays important roles in pre-mRNA splicing and nuclear export of RNA. As a candidate for the factor involved in these nuclear events we have previously purified an 80 kDa nuclear cap binding protein (NCBP) from a HeLa cell nuclear extract and isolated its full-length cDNA. In this report, in order to obtain a clue to the cellular functions of NCBP, we attempted to identify a factor(s) that interacts with NCBP. Using the yeast two-hybrid system we isolated three clones from a HeLa cell cDNA library. We designated the proteins encoded by these clones NIPs (NCBP interacting proteins). NIP1 and NIP2 have an RNP consensus-type RNA binding domain, whereas NIP3 contains a unique domain of Arg-Glu or Lys-Glu dipeptide repeats. We also show that NCBP requires NIP1 for binding to the cap structure. Possible roles of NIPs in cap-dependent nuclear processes are discussed. | lld:pubmed |
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| pubmed-article:7478990 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7478990 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7478990 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:7478990 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7478990 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:7478990 | pubmed:issn | 0305-1048 | lld:pubmed |
| pubmed-article:7478990 | pubmed:author | pubmed-author:OhnoMM | lld:pubmed |
| pubmed-article:7478990 | pubmed:author | pubmed-author:KataokaNN | lld:pubmed |
| pubmed-article:7478990 | pubmed:author | pubmed-author:ShimuraYY | lld:pubmed |
| pubmed-article:7478990 | pubmed:author | pubmed-author:ModaII | lld:pubmed |
| pubmed-article:7478990 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7478990 | pubmed:day | 25 | lld:pubmed |
| pubmed-article:7478990 | pubmed:volume | 23 | lld:pubmed |
| pubmed-article:7478990 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7478990 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7478990 | pubmed:pagination | 3638-41 | lld:pubmed |
| pubmed-article:7478990 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:7478990 | pubmed:year | 1995 | lld:pubmed |
| pubmed-article:7478990 | pubmed:articleTitle | Identification of the factors that interact with NCBP, an 80 kDa nuclear cap binding protein. | lld:pubmed |
| pubmed-article:7478990 | pubmed:affiliation | Department of Biophysics, Faculty of Science, Kyoto University, Japan. | lld:pubmed |
| pubmed-article:7478990 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7478990 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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