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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1981-3-17
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pubmed:abstractText |
Using four mouse tumor systems--leukemia L1210, i.m. mammary carcinoma 1142A, Lewis lung carcinoma, metastatic model of the mammary carcinoma 1142A--a combined treatment consisting of vincristine--cyclophosphamide--metrotrexate--5-fluorouracil is superior to a combined treatment with carminomycin--dibromodulcitol. The treatment with carminomycin and dibromodulcitol in each case alone causes therapeutic benefits being superior to a treatment with the combination carminomycin--dibromodulcitol. This result could be stated for all tumor systems used. Carminomycin showed the greatest effectivity against the leukemia L1210. A human tumor nude mouse system--ascitic mesothelioma 1503A--is presented which is suitable for chemotherapeutic experiments. First test results indicated an antineoplastic effectivity after daunoblastin treatment, but cyclophosphamide and carminomycin did not influence the life span.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0030-2414
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
37 Suppl 1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
34-41
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:7454199-Animals,
pubmed-meshheading:7454199-Antineoplastic Agents,
pubmed-meshheading:7454199-Drug Therapy, Combination,
pubmed-meshheading:7454199-Humans,
pubmed-meshheading:7454199-Leukemia L1210,
pubmed-meshheading:7454199-Lung Neoplasms,
pubmed-meshheading:7454199-Mammary Neoplasms, Experimental,
pubmed-meshheading:7454199-Mesothelioma,
pubmed-meshheading:7454199-Mice,
pubmed-meshheading:7454199-Mice, Nude,
pubmed-meshheading:7454199-Models, Biological,
pubmed-meshheading:7454199-Neoplasm Transplantation,
pubmed-meshheading:7454199-Neoplasms, Experimental,
pubmed-meshheading:7454199-Transplantation, Heterologous
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pubmed:year |
1980
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pubmed:articleTitle |
Recent results with clinically used antineoplastic drugs and drug combinations in vivo.
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pubmed:publicationType |
Journal Article
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