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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
11
|
| pubmed:dateCreated |
1981-3-17
|
| pubmed:abstractText |
After tritium labelling of silybin the time-dependent uptake of the flavonolignane derivative into rat liver was measured. Within the liver cells the distribution of silybin (and -metabolites) in cytosol, nuclear constituents and membrane material was determined and the accumulation of the flavonolignane derivative in cytosol and nuclear membranes confirmed by autoradiography. Within the nuclei a preferential binding on chromosomal proteins was found.
|
| pubmed:language |
ger
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Nov
|
| pubmed:issn |
0018-4888
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
361
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1751-6
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:7450686-Animals,
pubmed-meshheading:7450686-Autoradiography,
pubmed-meshheading:7450686-Cell Nucleus,
pubmed-meshheading:7450686-Cytosol,
pubmed-meshheading:7450686-Flavonoids,
pubmed-meshheading:7450686-Liver,
pubmed-meshheading:7450686-Male,
pubmed-meshheading:7450686-Membranes,
pubmed-meshheading:7450686-Nucleoproteins,
pubmed-meshheading:7450686-Protein Binding,
pubmed-meshheading:7450686-Rats,
pubmed-meshheading:7450686-Silymarin
|
| pubmed:year |
1980
|
| pubmed:articleTitle |
[Mechanism of silybin action, III. Resorption of the flavonolignane derivative silybin into rat liver cells (author's transl)].
|
| pubmed:publicationType |
Journal Article,
English Abstract
|