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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1981-3-17
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pubmed:abstractText |
A lipolytic substance in the ascites fluid of mice with Sarcoma 180, called toxohormone-L, was purified and characterized. The lipolytic activity of toxohormone-L was measured in vitro using rat adipose tissue slices. Toxohormone-L, purified approximately 90-fold from the ammonium sulfate fraction, gave a single band on polyacrylamide gel electrophoresis. Its molecular weight was about 75,000, and its isoelectric point was 4.7. Toxohormone-L is heat labile and nondialyzable, but, on its digestion with trypsin, an active fragment that was heat stable and dialyzable was produced. Toxohormone-L is a protein and is also present in the ascites fluid of patients with hepatoma and Grawitz's tumor.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0008-5472
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
41
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
284-8
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:7448767-Animals,
pubmed-meshheading:7448767-Endotoxins,
pubmed-meshheading:7448767-Exudates and Transudates,
pubmed-meshheading:7448767-Isoelectric Point,
pubmed-meshheading:7448767-Lipolysis,
pubmed-meshheading:7448767-Mice,
pubmed-meshheading:7448767-Molecular Weight,
pubmed-meshheading:7448767-Neoplasm Proteins,
pubmed-meshheading:7448767-Sarcoma, Experimental,
pubmed-meshheading:7448767-Triglycerides
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pubmed:year |
1981
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pubmed:articleTitle |
Purification and characterization of a lipolytic factor (toxohormone-L) from cell-free fluid of ascites sarcoma 180.
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pubmed:publicationType |
Journal Article
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