Linked Life Data

7444221

Source:http://linkedlifedata.com/resource/pubmed/id/7444221

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1981-2-24
pubmed:abstractText
Pattern of breathing and mouth occlusion pressure have been investigated during a 6-day sojourn at an altitude of 3457 m in six resting subjects breathing ambient air or an hyperoxic mixture. It has been shown that ventilation increases and alveolar PCO2 decreases, both variables reaching a steady-state after about 4 days at altitude. Changes in ventilation are caused by modifications, at first, in the timing component of the respiratory cycle and later on, in the mean inspiratory airflow. This suggests that the output of the respiratory center is qualitatively modified during the acclimatization period. Mouth occlusion pressure, an index of neuromuscular inspiratory drive, increased on the first day at altitude, remaining constant thereafter. The mean inspiratory flow did not change on the first day, but progressively increased in the subsequent 3 days. The observation that flow increased in the face of a constant neuromuscular inspiratory drive suggests that during acclimatization to altitudes, the progressive increase in ventilation is due to changes in mechanics of the ventilatory pump rather than changes in central neural drive.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0034-5687
pubmed:author
pubmed:issnType
Print
pubmed:volume
40
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
365-77
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Pattern of breathing and mouth occlusion pressure during acclimatization to high altitude.
pubmed:publicationType
Journal Article