Linked Life Data

7433923

Source:http://linkedlifedata.com/resource/pubmed/id/7433923

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1981-1-29
pubmed:abstractText
Data are presented on the absorption, antibacterial activity, clinical efficacy and side effects of cefuroxime in 33 cases with proven bacterial infection in soft tissues and in patients with septicaemia. The drug was administered mainly intramuscularly (i.m.) but also intravenously (i.v.). Peak serum concentrations 1 h after an injection of 750 mg cefuroxime i.m. were between 16-25 mug/ml. After 8 h the levels were mostly < 4 mug/ml in patients with normal renal function. I.v. injection gave only slightly higher maximum serum level obtained was approximately 40 mug/ml. No accumulation of the drug occurred in patients with normal renal function. Cefuroxime was active against all the gram-positive bacteria isolated from our patients as well as most of the gram-negatives. The clinical effect was satisfactory in 96%. The drug was well tolerated. Side effects were slight and relatively few.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0036-5548
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
227-30
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Cefuroxime in soft tissue infections and septicaemia.
pubmed:publicationType
Journal Article