Linked Life Data

7422703

Source:http://linkedlifedata.com/resource/pubmed/id/7422703

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1980-12-18
pubmed:abstractText
Young adult male rhesus monkeys received bilateral lesions in the anteromedial lateral hypothalamus. During the year of observation following surgery the animals were hyperphagic and became markedly obese. The mean increase in body weight averaged 66% more for the experimental animals than for the controls. Analyses of catecholamine concentrations in 12 brain regions at the time of sacrifice revealed consistently lower concentrations of norepinephrine (averaging 51% of control) in the frontal cortex of the obese animals as well as a more variable decrease in norepinephrine in the caudate and striatum. There was no consistent effect of the lesions on dopamine in any of the regions studied. There was no obvious relationship between regional catecholamine levels and weight gain within the experimental group.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0091-3057
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
461-5
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Reduced forebrain norepinephrine in rhesus monkeys made obese by hypothalamic lesions.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't