Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1980-11-20
pubmed:abstractText
Rat hepatocyte fractions enriched with lysosomes were studied one hour and 7 days after vast thermal burn of the skin. The ratio of free catepsine D activity to its total activity served as an index of lysosomal membrane resistance. The lipid composition was assayed by thin layer chromatography on silica gel. Material increase in lysosomal membrane permeability was recorded both one hour and 7 days after burn. Significant shifts were also seen in the composition of neutral lipids and phospholipids. Burn gave rise to the triglyceride fraction that was not present in the control. Among phospholipids the most labile were minor fractions, that is those of sphyngomyelin, phosphatidylinosite and phosphatidylserine. The changes in the lipids are considered as essential for destructive alterations in the liver in burn disease.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0365-9615
pubmed:author
pubmed:issnType
Print
pubmed:volume
89
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
60-1
pubmed:dateRevised
2008-10-8
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
[Alteration of the permeability and composition of liver cell lysosomal membranes after a thermal burn].
pubmed:publicationType
Journal Article, English Abstract