Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3-4
pubmed:dateCreated
1980-11-24
pubmed:abstractText
The conditions required for the counterion induced collapse of T7 bacteriophage DNA are briefly reviewed. Using Manning's counterion condensation theory we calculate a striking unity among collapse conditions: collapse occurs when from 89% to 90% of the DNA phosphate charges are neutralized by condensed counterions. The forces involved in collapsed DNA are investigated with emphasis on electrostatic repulsion. It is concluded that polyelectrolyte repulsion is the dominant force opposing collapse. Comparison of the results or polyelectrolyte repulsion calculation made using numerical methods and the Poisson-Boltzmann equation, with values of the attractive energies due to London dispersion interactions, leads to the conclusion that dispersion forces are probably large enough to cause collapse when the repulsions have been reduced by the presence of multivalent counterions.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0301-4622
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
339-43
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Polyelectrolyte effects in DNA condensation by polyamines.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.