Linked Life Data

7371200

Source:http://linkedlifedata.com/resource/pubmed/id/7371200

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1980-7-22
pubmed:abstractText
A high resolution two-dimensional electrophoresis technique (Iso-Dalt) has been employed to characterise the protein components of freshly drawn human serum and various human- and animal-based quality control sera. This technique allows a direct comparison to be made between the protein components of different materials. Similarities have been demonstrated between the protein components (protein matrix) of freshly drawn human serum and human-, equine- and bovine-based control sera, though some differences existed between sera from these three sources, mainly in the acidic high molecular weight quadrant and the lipoprotein and haptoglobin regions. The Iso-Dalt technique also revealed differences in the protein matrices of the various human-based quality control sera tested. Differences attributable to manufacturing technique were also discernible by inspection of the two-dimensional maps of the protein matrices. Although characterisation and comparison of protein components of the matrix of serum is difficult, the Iso-Dalt technique has proved a valuable tool in this characterisation and the subsequent assessment of the similarity of quality control sera to human serum. This type of information is valuable when considering the suitability of human- or animal-based sera for use in internal and external quality control procedures.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0009-8981
pubmed:author
pubmed:issnType
Print
pubmed:day
25
pubmed:volume
103
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
219-28
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Characterisation of the protein matrix of quality control sera by a high resolution two-dimensional electrophoresis technique.
pubmed:publicationType
Journal Article, Comparative Study