Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1982-5-12
pubmed:abstractText
The activity of 5-formyl-tetrahydrofolate cyclodehydrase has been studied cytochemically in leucocytes of children with acute leukaemia. Comparison of enzymatic activity in the same types of cells showed no significant variation between normal controls and the patients with acute leukaemia. The blast cells were weakly positive or negative. This finding is of very interest as the blast cells are capable of division. Probably the enzyme appears in the blast cells at some stage of the cell cycle. 2 populations of lymphocytes were observed, 1 positive with a few granules and 1 negative. A reduction of enzyme activity was observed after prophylactic cranial irradiation and methotrexate decreased enzyme activity in some patients.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0036-553X
pubmed:author
pubmed:issnType
Print
pubmed:volume
26
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
393-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Cytochemical demonstration of 5-formyl-tetrahydrofolate cyclodehydrase activity in leucocytes of patients with acute leukaemia.
pubmed:publicationType
Journal Article