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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
1982-4-12
|
| pubmed:abstractText |
An HPLC method for the separate determination of chloroquine and its major metabolites has been developed. Separation was on an octadecyl RP column. Fluorimetric detection followed after on-line post-column buffering of the mobile phase to pH = 9.25. The method is highly selective for the compounds of interest with a detection limit down to 1 ng/ml. Preliminary data on the pharmacokinetics of chloroquine are reported, as obtained with this method. Kinetic parameters were estimated with the aid of the non-linear regression computer programme NON-LIN.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Dec
|
| pubmed:issn |
0167-6555
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
18
|
| pubmed:volume |
3
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
263-7
|
| pubmed:dateRevised |
2008-2-25
|
| pubmed:meshHeading | |
| pubmed:year |
1981
|
| pubmed:articleTitle |
HPLC-analysis and preliminary pharmacokinetic parameter estimations of chloroquine.
|
| pubmed:publicationType |
Journal Article
|