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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1982-4-12
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pubmed:abstractText |
The frequency of transformation induced in plateau phase 10T 1/2 cells by a single dose of X-rays decreased as a function of time during the early post-irradiation period (0 approximately 6 hr), and then tended to increase during the late post-irradiation period (7 approximately 48 hr). The extent of reduction, as measured in terms of the ratio (6 hr/0 hr value) of transformation, ranged from 0.2 to 1.1, depending upon the batch of serum which was used for pre-irradiation culture. The above findings, together with the results of a serum-free experiment, suggested that a factor affecting such reduction is present in sera. Transformation frequency depended not only on the serum used for pre-irradiation culture but also on the serum for assay culture. To maintain internal consistence of results from a series of experiments, the use of a single batch of serum is essential.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0016-450X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
72
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
762-8
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:7327374-Animals,
pubmed-meshheading:7327374-Cell Division,
pubmed-meshheading:7327374-Cell Line,
pubmed-meshheading:7327374-Cell Survival,
pubmed-meshheading:7327374-Cell Transformation, Neoplastic,
pubmed-meshheading:7327374-Clone Cells,
pubmed-meshheading:7327374-DNA Repair,
pubmed-meshheading:7327374-Embryo, Mammalian,
pubmed-meshheading:7327374-Kinetics,
pubmed-meshheading:7327374-Mice,
pubmed-meshheading:7327374-Mice, Inbred C3H
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pubmed:year |
1981
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pubmed:articleTitle |
Radiation-induced transformation of 10T 1/2 mouse cells in the plateau phase: post-irradiation changes and serum dependence.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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