Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1982-4-12
pubmed:abstractText
The frequency of transformation induced in plateau phase 10T 1/2 cells by a single dose of X-rays decreased as a function of time during the early post-irradiation period (0 approximately 6 hr), and then tended to increase during the late post-irradiation period (7 approximately 48 hr). The extent of reduction, as measured in terms of the ratio (6 hr/0 hr value) of transformation, ranged from 0.2 to 1.1, depending upon the batch of serum which was used for pre-irradiation culture. The above findings, together with the results of a serum-free experiment, suggested that a factor affecting such reduction is present in sera. Transformation frequency depended not only on the serum used for pre-irradiation culture but also on the serum for assay culture. To maintain internal consistence of results from a series of experiments, the use of a single batch of serum is essential.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0016-450X
pubmed:author
pubmed:issnType
Print
pubmed:volume
72
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
762-8
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Radiation-induced transformation of 10T 1/2 mouse cells in the plateau phase: post-irradiation changes and serum dependence.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't