Linked Life Data

7322138

Source:http://linkedlifedata.com/resource/pubmed/id/7322138

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
1982-3-13
pubmed:abstractText
In 11 obese children aged 11,9 +/- 1,3 years total cholesterol (C), triglycerides (TG), HDL-C, LDL-C and apolipoprotein B (Apo B) were estimated in serum after 3 weeks of hypocaloric diet (800 kcal, kJ). In vitro platelet function was evaluated using the tests of ADP-induced aggregation and platelet sensitivity to prostacyclin. The in vivo platelet activity was judged by estimating plasma levels of beta-thromboglobuline (beta-TG) and platelet factor 4 (PF4). A mean weight loss of 5,7 +/- 1,8 kg was observed. Before diet, serum-C, TG and lipoprotein-C concentrations were found to be within the so called "normal range". After three weeks of diet we observed a significant decrease of total-C, which could be accounted for by a decline in the atherogenic LDL-C; furthermore Apo B levels significantly decreased. Concerning the tests of platelet function only for beta-TG and PF 4 a marked decline (to about 50% of the initial values) could be seen. These preliminary results and changes in the lipoprotein are discussed in connection with a possible reduction of the risk for the development of atherosclerotic lesions.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0026-9298
pubmed:author
pubmed:issnType
Print
pubmed:volume
129
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
623-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
[Effect of body weight reduction on platelet function and serum lipoproteins in obese children (author's transl)].
pubmed:publicationType
Journal Article, English Abstract