rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
2
|
pubmed:dateCreated |
1981-11-18
|
pubmed:abstractText |
Human chest clearance of Teflon particles with an aerodynamic diameter of 4.7 micrometers tagged with 198Au or 111In was studied with two apparatuses and two gamma-ray spectrometers for the external detection of the activity deposited in the respiratory tract. Approximately the same chest retention function was measured with two gamma-ray spectrometers when the subjects inhaled equal aerosols under equal breathing conditions. The long-term clearance rate following the short-term elimination of particles from ciliated airways was slower for Teflon particles (mean half-time 105 days for 111In-labeled particles and 128 days for 198Au-labeled particles) than for iron oxide particles of the same size (mean half-time about 60 days). It is suggested that insoluble particles of this size studied are cleared with a half-time of about 120 days within the first 2 weeks after completion of mucociliary clearance. Regional deposition did not differ between the iron oxide and Teflon particles.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0190-2148
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
2
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
131-9
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:7274177-Adult,
pubmed-meshheading:7274177-Aerosols,
pubmed-meshheading:7274177-Gold Radioisotopes,
pubmed-meshheading:7274177-Half-Life,
pubmed-meshheading:7274177-Humans,
pubmed-meshheading:7274177-Indium,
pubmed-meshheading:7274177-Iron,
pubmed-meshheading:7274177-Isotope Labeling,
pubmed-meshheading:7274177-Lung,
pubmed-meshheading:7274177-Male,
pubmed-meshheading:7274177-Metabolic Clearance Rate,
pubmed-meshheading:7274177-Middle Aged,
pubmed-meshheading:7274177-Particle Size,
pubmed-meshheading:7274177-Polytetrafluoroethylene,
pubmed-meshheading:7274177-Radioisotopes,
pubmed-meshheading:7274177-Spectrometry, Gamma,
pubmed-meshheading:7274177-Time Factors
|
pubmed:year |
1981
|
pubmed:articleTitle |
Intercomparison of regional deposition of aerosol particles in the human respiratory tract and their long-term elimination.
|
pubmed:publicationType |
Journal Article,
Comparative Study
|