Linked Life Data

7270948

Source:http://linkedlifedata.com/resource/pubmed/id/7270948

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1981-10-25
pubmed:abstractText
The purpose of this study was to define the EEG changes produced in humans by fentanyl 30-70 microgram/kg during cardiac surgery. The authors have also assessed awareness in the patients. Thirty-nine patients were studied; oral lorazepam or intramuscular morphine was used as premedication. Anesthesia was induced with intravenous injection of fentanyl over 2 min and the patients were ventilated with either air/O2 (24 patients) or N2O/O2 (15 patients). The EEGs recorded until the start of cardiopulmonary bypass were visually analyzed, classified into EEG stage, and plotted graphically as narcograms. Computerized 3-dimensional power spectral analysis and wide band spectral analysis were carried out on representative EEGs. The EEG effects of fentanyl are consistent and are characterized by high-voltage slow delta waves. Nitrous oxide had no effect on the EEG responses to fentanyl. Computer analysis confirmed the visual interpretation. There was no incidence of awareness. The authors conclude from this study that fentanyl after premedication is a suitable drug for providing unconsciousness, analgesia, and amnesia during cardiac surgery.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0003-3022
pubmed:author
pubmed:issnType
Print
pubmed:volume
55
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
203-11
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Effects of high-dose fentanyl anesthesia on the electroencephalogram.
pubmed:publicationType
Journal Article