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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
16
|
| pubmed:dateCreated |
1981-10-25
|
| pubmed:abstractText |
1. There are two 2,4-dienoyl-CoA reductases (EC 1.3.1.-) (formerly called 4-enoyl-CoA reductase, Eur. J. Biochem. (1978) 91, 533-544) in rat liver, one in mitochondria and another one in peroxisomes. 2. Treatment of rats with clofibrate increases the activities of the 2,4-dienoyl-CoA reductases in both cell organelles. 3. Isolated peroxisomes metabolize 4-cis-decenoyl-CoA, a metabolite of linoleic acid, via the 2,4-dienoyl-CoA reductase pathway. 4. From these results it is concluded that peroxisomes have the enzymatic apparatus necessary for the degradation of unsaturated fatty acids.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Aug
|
| pubmed:issn |
0021-9258
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
25
|
| pubmed:volume |
256
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
8259-62
|
| pubmed:dateRevised |
2009-11-19
|
| pubmed:meshHeading |
pubmed-meshheading:7263650-Animals,
pubmed-meshheading:7263650-Clofibrate,
pubmed-meshheading:7263650-Fatty Acid Desaturases,
pubmed-meshheading:7263650-Fatty Acids, Unsaturated,
pubmed-meshheading:7263650-Liver,
pubmed-meshheading:7263650-Male,
pubmed-meshheading:7263650-Microbodies,
pubmed-meshheading:7263650-Organoids,
pubmed-meshheading:7263650-Rats,
pubmed-meshheading:7263650-Subcellular Fractions
|
| pubmed:year |
1981
|
| pubmed:articleTitle |
Degradation of unsaturated fatty acids in peroxisomes. Existence of a 2,4-dienoyl-CoA reductase pathway.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|