| pubmed-article:7260273 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7260273 | lifeskim:mentions | umls-concept:C0004927 | lld:lifeskim |
| pubmed-article:7260273 | lifeskim:mentions | umls-concept:C0205132 | lld:lifeskim |
| pubmed-article:7260273 | lifeskim:mentions | umls-concept:C1552961 | lld:lifeskim |
| pubmed-article:7260273 | lifeskim:mentions | umls-concept:C0205460 | lld:lifeskim |
| pubmed-article:7260273 | lifeskim:mentions | umls-concept:C2347299 | lld:lifeskim |
| pubmed-article:7260273 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:7260273 | pubmed:dateCreated | 1981-10-25 | lld:pubmed |
| pubmed-article:7260273 | pubmed:abstractText | The linear phenomenological equations of nonequilibrium thermodynamics are limited theoretically to near equilibrium although a number of biological systems have been shown to exhibit a "linear" relationship between steady-state flows and conjugate thermodynamic forces outside the range of equilibrium. We have found a multidimensional inflection point which can exist well outside the range of equilibrium around with enzyme-catalyzed reactions exhibit "linear" behavior between the logarithm of reactant concentrations and enzyme catalyzed flows. A set of sufficient conditions has been derived which can be applied to any enzyme mechanism to determine whether a multidimensional inflection point exists. The conditions do not appear overly restrictive and may be satisfied by a large variety of coupled enzyme reactions. It is thus possible that the linearity observed in some biological systems may be explained in terms of enzyme operating near this multidimensional point. | lld:pubmed |
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| pubmed-article:7260273 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7260273 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7260273 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7260273 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7260273 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7260273 | pubmed:month | May | lld:pubmed |
| pubmed-article:7260273 | pubmed:issn | 0006-3495 | lld:pubmed |
| pubmed-article:7260273 | pubmed:author | pubmed-author:StanleyH EHE | lld:pubmed |
| pubmed-article:7260273 | pubmed:author | pubmed-author:RothschildK... | lld:pubmed |
| pubmed-article:7260273 | pubmed:author | pubmed-author:EssigAA | lld:pubmed |
| pubmed-article:7260273 | pubmed:author | pubmed-author:ElliasS ASA | lld:pubmed |
| pubmed-article:7260273 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7260273 | pubmed:volume | 30 | lld:pubmed |
| pubmed-article:7260273 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7260273 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7260273 | pubmed:pagination | 209-30 | lld:pubmed |
| pubmed-article:7260273 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:7260273 | pubmed:meshHeading | pubmed-meshheading:7260273-... | lld:pubmed |
| pubmed-article:7260273 | pubmed:meshHeading | pubmed-meshheading:7260273-... | lld:pubmed |
| pubmed-article:7260273 | pubmed:meshHeading | pubmed-meshheading:7260273-... | lld:pubmed |
| pubmed-article:7260273 | pubmed:meshHeading | pubmed-meshheading:7260273-... | lld:pubmed |
| pubmed-article:7260273 | pubmed:meshHeading | pubmed-meshheading:7260273-... | lld:pubmed |
| pubmed-article:7260273 | pubmed:year | 1980 | lld:pubmed |
| pubmed-article:7260273 | pubmed:articleTitle | Nonequilibrium linear behavior of biological systems. Existence of enzyme-mediated multidimensional inflection points. | lld:pubmed |
| pubmed-article:7260273 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:7260273 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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