|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2
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|
pubmed:dateCreated |
1981-9-15
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|
pubmed:abstractText |
The authors found that the phosphororganic pesticide neguvon in a dose of 200 mg/kg of body weight diminished the content of dopamine in the striatum of white rats. This effect was increased after daily administration of the same dose for a period of 5 days. The reactivator of cholinesterase TMB-4 and H-choline blocker tropacine prevented this effect. They discussed the connection between the changes in the content of dopamine and modulating role of presynaptic choline receptors of H- and M- types in the dopaminergic terminals of the striatum.
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pubmed:language |
bul
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:issn |
0367-0643
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
20
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
62-6
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:7250022-Animals,
pubmed-meshheading:7250022-Benactyzine,
pubmed-meshheading:7250022-Brain,
pubmed-meshheading:7250022-Cholinesterase Reactivators,
pubmed-meshheading:7250022-Corpus Striatum,
pubmed-meshheading:7250022-Diphenylacetic Acids,
pubmed-meshheading:7250022-Dopamine,
pubmed-meshheading:7250022-Male,
pubmed-meshheading:7250022-Rats,
pubmed-meshheading:7250022-Time Factors,
pubmed-meshheading:7250022-Trichlorfon,
pubmed-meshheading:7250022-Trimedoxime,
pubmed-meshheading:7250022-Tropanes
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pubmed:year |
1981
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|
pubmed:articleTitle |
[Effect of the organophosphorus compound neguvon on the dopamine content in the rat brain].
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pubmed:publicationType |
Journal Article,
English Abstract
|
