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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
1979-2-23
|
| pubmed:abstractText |
Counts of neuronal nucleoli were made in the dorsal motor vagal nucleus (DMV) of the adult rabbit 10, 18, 70 and 90 days following unilateral cervical vagotomy. The structural characteristics of nerve cell bodies in the DMV were studied electron microscopically 2--90 days after cervical vagotomy. The nucleolar counts indicated that 20% of the large DMV neurones had disappeared ipsilateral to the operation 10 days postoperatively (p.o.), 65% 18 days p.o. and 70% 70 and 90 days p.o. No loss of small neurones was found. Large neurones ipsilateral to the operation showed nuclear displacement, infoldings of the nuclear membrane and disappearance of granular endoplasmic reticulum beginning 4 days p.o. and being prominent 6--18 days p.o. At the peak of the response, 10--18 days p.o., reacting neurones showed nucleolar condensation and vacuolation, the appearance of intranuclear electron-dense particles, extensive accumulation of intracytoplasmic lipid droplets, increased numbers of microtubules and neurofilaments, focal mitochondrial aggregates, and widespread mitochondrial degeneration. Ten to 21 days p.o. degenerating neurones were observed. After 30 days p.o. survival a partial recovery of surviving large DMV neurones seemed to have taken place. The findings are interpreted as indications of distubed protein metabolism, oxidative metabolism and intraneuronal transport in the axotomized DMV neurones. The unique response of these neurones compared to previously studied peripherally projecting neurones is emphasized.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0305-1846
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
4
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
323-41
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:724089-Animals,
pubmed-meshheading:724089-Brain Stem,
pubmed-meshheading:724089-Cell Nucleolus,
pubmed-meshheading:724089-Endoplasmic Reticulum,
pubmed-meshheading:724089-Female,
pubmed-meshheading:724089-Functional Laterality,
pubmed-meshheading:724089-Golgi Apparatus,
pubmed-meshheading:724089-Lipid Metabolism,
pubmed-meshheading:724089-Male,
pubmed-meshheading:724089-Microtubules,
pubmed-meshheading:724089-Mitochondria,
pubmed-meshheading:724089-Nerve Regeneration,
pubmed-meshheading:724089-Rabbits,
pubmed-meshheading:724089-Vagotomy
|
| pubmed:articleTitle |
Fine structural changes in nerve cell bodies of the adult rabbit dorsal motor vagal nucleus during axon reaction.
|
| pubmed:publicationType |
Journal Article
|