Linked Life Data

7237249

Source:http://linkedlifedata.com/resource/pubmed/id/7237249

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1981-8-27
pubmed:abstractText
The effects of hemorrhage on the febrile response of the sheep was examined because hemorrhage is a potent stimulant for arginine vasopressin (AVP) release into cerebrospinal fluid and blood. Removal of 20% of the estimated blood volume of the conscious sheep led to small physiologic changes and significantly decreased fevers in response to bacterial endotoxin. Mean arterial blood pressure decreased in hemorrhaged febrile sheep to a significantly greater extent than in nonhemorrhaged febrile sheep. AVP levels were considerably greater in the blood of hemorrhaged febrile sheep than in nonhemorrhaged febrile sheep and the concentrations correlated with the magnitude of the decrease in fever. Sheep hemorrhaged in the cold had changes in body temperature similar to control sheep. These experiments support the hypothesis that AVP may be an antipyretic neuromodulator.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0008-4212
pubmed:author
pubmed:issnType
Print
pubmed:volume
59
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
324-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Effect of hemorrhage on fever: the putative role of vasopressin.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't