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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
1981-6-13
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pubmed:abstractText |
In 45 patients with radiologically and endoscopically/histologically proven Crohn's disease the partial functions of the anterior pituitary gland were measured prior to steroid therapy. No deficiencies were observed with respect to cortico-, thyro-, gonado-, and somatotropic functions. In 25 out of 40 patients (63%) the typical diurnal rhythm of cortisol secretion was absent when assessed by a distinctly elevated 6 p.m. cortisol serum level. In about one fourth of 22 patients T3-RIA was reduced, indicating deficiency of conversion from T4 to T3. Six (43%) out of 14 males showed reduced basal testosterone levels at 8 a.m. and 6 p.m. which, in 4 out of 14 cases, did not increase sufficiently in response to HCG. The basal LH-level was elevated in 9 (50%) of 18 males. The lack of diurnal rhythm of cortisol secretion and primary insufficiency of Leydig's cells did not correlate with the activity of the disease.
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pubmed:language |
ger
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0036-7672
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
14
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pubmed:volume |
111
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
214-20
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7221527-Adolescent,
pubmed-meshheading:7221527-Adult,
pubmed-meshheading:7221527-Body Weight,
pubmed-meshheading:7221527-Chorionic Gonadotropin,
pubmed-meshheading:7221527-Crohn Disease,
pubmed-meshheading:7221527-Female,
pubmed-meshheading:7221527-Growth Disorders,
pubmed-meshheading:7221527-Humans,
pubmed-meshheading:7221527-Hydrocortisone,
pubmed-meshheading:7221527-Male,
pubmed-meshheading:7221527-Middle Aged,
pubmed-meshheading:7221527-Pituitary Gland, Anterior,
pubmed-meshheading:7221527-Sexual Maturation,
pubmed-meshheading:7221527-Testosterone,
pubmed-meshheading:7221527-Triiodothyronine
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pubmed:year |
1981
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pubmed:articleTitle |
[Endocrinologic findings in Crohn's disease].
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pubmed:publicationType |
Journal Article,
English Abstract
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