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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1981-6-13
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pubmed:abstractText |
Athymic nude mice (nu/nu) were significantly more susceptible to pneumonia due to the agent of mouse pneumonitis (MoPn), Chlamydia trachomatis, than their heterozygous (nu/+) littermates, as judged both by a greater mortality and a decreased ability to rid their lungs of the infection. Nu/nu mice did not produce significant antibody to the MoPn agent, whereas nu/+ mice did. Thymic transplantation rendered nu/nu mice significantly more resistant to the MoPn agent than nu/nu controls. Resistance to the MoPn agent and production of specific antibody to the MoPn agent were dependent on thymus-derived cells.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0022-1899
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
143
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
238-41
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:7217718-Animals,
pubmed-meshheading:7217718-Chlamydia Infections,
pubmed-meshheading:7217718-Disease Susceptibility,
pubmed-meshheading:7217718-Female,
pubmed-meshheading:7217718-Heterozygote,
pubmed-meshheading:7217718-Homozygote,
pubmed-meshheading:7217718-Immunity, Cellular,
pubmed-meshheading:7217718-Immunocompetence,
pubmed-meshheading:7217718-Male,
pubmed-meshheading:7217718-Mice,
pubmed-meshheading:7217718-Mice, Nude,
pubmed-meshheading:7217718-Pneumonia,
pubmed-meshheading:7217718-Thymectomy
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pubmed:year |
1981
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pubmed:articleTitle |
Pneumonia due to Chlamydia trachomatis in the immunocompromised (nude) mouse.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
|