Linked Life Data

7202222

Source:http://linkedlifedata.com/resource/pubmed/id/7202222

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1982-10-29
pubmed:abstractText
The effect of both intrahypothalamic and systemic administration of guanosine triphosphate (GTP) on lordosis behavior was studied in ovariectomized and ovariectomized-adrenalectomized, estrogen-primed rats (estradiol benzoate, 4 micrograms). This estrogen dose per se induced only weak or no lordosis behavior. Injection of GTP into the medial hypothalamic area (100 micrograms in 2.5 microliters) elicited lordosis behavior with relatively short latency in 6 out of 7 rats. Systemic administration of GTP in a dose range of 0.8 mg to 5.0 mg to ovariectomized estrogen-primed rats, stimulated intense lordosis behavior in all subjects. Weak lordosis responses were displayed within the first 12 hr after GTP injection, but as 48 hr all rats were highly estrous. Lordosis behavior remained for up to eight days, its duration being related to the dose of GTP administered. GTP (2 mg) induced lordosis behavior in ovariectomized, adrenalectomized estrogen-primed rats, thus excluding the participation of adrenal steroids in this effect. The results are interpreted in terms of the stimulation of adenyl cyclase-cAMP systems by GTP.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0031-9384
pubmed:author
pubmed:issnType
Print
pubmed:volume
28
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1073-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Induction of female sexual behavior by GTP in ovariectomized estrogen primed rats.
pubmed:publicationType
Journal Article