Linked Life Data

7174907

Source:http://linkedlifedata.com/resource/pubmed/id/7174907

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1983-2-14
pubmed:abstractText
The insula sends neural efferents to cortical areas from which it receives reciprocal afferent projections. A collective consideration of afferents and efferents indicates that the insula has connections with principal sensory areas in the olfactory, gustatory, somesthetic (SI and SII), and auditory (AI and AII) modalities. There are additional connections with association areas for the visual (TEm), auditory (supratemporal plane), and somesthetic (posterior parietal cortex) modalities; with paramotor cortex (area 6 and perhaps MII); with polymodal association cortex; and with a wide range of paralimbic areas in the orbital, temporopolar, and cingulate areas. The topographic distribution of these connections suggests that the posterodorsal insula is specialized for auditory-somesthetic-skeletomotor function whereas the anteroventral insula is related to olfactory-gustatory-autonomic function. Most of the insula, especially its anteroventral portions, have extensive interconnections with limbic structures. Through its connections with the amygdala, the insula provides a pathway for somatosensory, auditory, gustatory, olfactory, and visceral sensations to reach the limbic system. The cortical areas connected with the granular sector of the insula are also granular in architecture whereas virtually all the connections of the agranular insula arise from allocortical, agranular, or dysgranular areas. Thus, there is a correspondence between the architecture of insular sectors and the areas with which they have connections. The insula is heavily interconnected with temporopolar and lateral orbital areas. Furthermore, many cortical connections of the lateral orbital cortex are quite similar to those of the insula. These common connectivity patterns support the conclusion, based on architectonic observations, that the insulo-orbito-temporopolar component of the paralimbic brain should be considered as an integrated unit of cerebral organization.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0021-9967
pubmed:author
pubmed:issnType
Print
pubmed:day
20
pubmed:volume
212
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
38-52
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Insula of the old world monkey. III: Efferent cortical output and comments on function.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't