Linked Life Data

7170603

Source:http://linkedlifedata.com/resource/pubmed/id/7170603

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
Pt 3
pubmed:dateCreated
1983-6-17
pubmed:abstractText
Preservation of the endothelial lining of veins during preparation as grafts appears likely to play a critical role in subsequent early graft patency rates. 82 cephalic veins from 41 dogs were divided into 6 major groups by the type of heparinized vein preservation solution used. Veins were soaked for 5 min. or 1 hr. at either 10 degrees C or 20 degrees C in one of the following solutions with or without 60mg/100 ml of papaverine added: Plasma-Lyte 148 autologous blood, or Fluosol DA (an oxygenated perfluorocarbon emulsion). A segment was removed from each vein as soon as it was dissected free and perfused with fixative at 30 mm Hg as a control. In 4 additional dogs both cephalic veins were perfusion fixed in situ as further controls. SEM examination of the vein grafts' luminal surface after storage in the various preservation solutions showed that the greatest single cause of endothelial cell damage or loss was the extent to which the vein was permitted to undergo vigorous contraction during preparation and storage prior to use as an arterial graft. Preparation solutions which contained the smooth muscle cell relaxant papaverine, therefore, minimized endothelial protrusion and loss. In this regard Plasma-Lyte plus papaverine maintained at 20 degrees C was the most satisfactory of the solutions tested.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0586-5581
pubmed:author
pubmed:issnType
Print
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1221-8
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Scanning electron microscopic study of endothelial damage resulting from vein graft contraction during preparation.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.