pubmed-article:7170064 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:7170064 | lifeskim:mentions | umls-concept:C0006104 | lld:lifeskim |
pubmed-article:7170064 | lifeskim:mentions | umls-concept:C0597295 | lld:lifeskim |
pubmed-article:7170064 | lifeskim:mentions | umls-concept:C0042285 | lld:lifeskim |
pubmed-article:7170064 | lifeskim:mentions | umls-concept:C0242485 | lld:lifeskim |
pubmed-article:7170064 | lifeskim:mentions | umls-concept:C0205276 | lld:lifeskim |
pubmed-article:7170064 | lifeskim:mentions | umls-concept:C1521828 | lld:lifeskim |
pubmed-article:7170064 | lifeskim:mentions | umls-concept:C1519941 | lld:lifeskim |
pubmed-article:7170064 | lifeskim:mentions | umls-concept:C1510991 | lld:lifeskim |
pubmed-article:7170064 | pubmed:issue | 12 | lld:pubmed |
pubmed-article:7170064 | pubmed:dateCreated | 1983-6-10 | lld:pubmed |
pubmed-article:7170064 | pubmed:abstractText | Following the injection of 4-day old rats with 150 mM L-[3,4-3H]valine (10 mumol/g, IP) the incorporation of 3H into protein was linear 2 hours. Valine specific activity in the brain acid-soluble fraction was constant between 30 and 120 min after injection with a mean value of 82.3% of the injectate. Significant amounts of tritated metabolites accumulated in the brain acid-soluble fraction (41.4% of radioactivity at 120 min) but do not prove an impediment to measuring rates of protein synthesis. The rate of protein synthesis in cerebral cortex of the 4-day old rat was measured by quantitative autoradiography using [3H]valine and 3H-sensitive film. The measured rate shows excellent agreement with that found previously using L-[1-14C]valine. Our results suggest that [3H]valine can be a useful precursor to measure local rates of brain protein synthesis by quantitative autoradiography. | lld:pubmed |
pubmed-article:7170064 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7170064 | pubmed:language | eng | lld:pubmed |
pubmed-article:7170064 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7170064 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:7170064 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7170064 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7170064 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7170064 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:7170064 | pubmed:month | Dec | lld:pubmed |
pubmed-article:7170064 | pubmed:issn | 0364-3190 | lld:pubmed |
pubmed-article:7170064 | pubmed:author | pubmed-author:WasterlainC... | lld:pubmed |
pubmed-article:7170064 | pubmed:author | pubmed-author:DwyerB EBE | lld:pubmed |
pubmed-article:7170064 | pubmed:author | pubmed-author:DonatoniPP | lld:pubmed |
pubmed-article:7170064 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:7170064 | pubmed:volume | 7 | lld:pubmed |
pubmed-article:7170064 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:7170064 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:7170064 | pubmed:pagination | 1507-14 | lld:pubmed |
pubmed-article:7170064 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
pubmed-article:7170064 | pubmed:meshHeading | pubmed-meshheading:7170064-... | lld:pubmed |
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pubmed-article:7170064 | pubmed:meshHeading | pubmed-meshheading:7170064-... | lld:pubmed |
pubmed-article:7170064 | pubmed:year | 1982 | lld:pubmed |
pubmed-article:7170064 | pubmed:articleTitle | Measurement of local rates of brain protein synthesis by quantitative autoradiography: validation with L-[3H]valine. | lld:pubmed |
pubmed-article:7170064 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:7170064 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
pubmed-article:7170064 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |