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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1983-6-17
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pubmed:abstractText |
The pH of bathing media containing acetate increased substantially during a 90-min incubation of renal cortex slices from rats and rabbits and did not achieve a steady state after 5 h. Alkalinization of the medium was markedly depressed by cold (0 degree C) and nearly abolished by incubation under 100% N2. Ammonia synthesis did not appear to be an important additional source of base. Incubation of tissue from either species in acetate-free medium reduced but did not abolish base production. Acetazolamide further reduced base production by rat kidney. It was concluded that a portion of the base added to the medium by rat renal tissue reflects the operation of a transport process that separates hydrogen and hydroxyl ions and may be the same one that normally secretes hydrogen ion into tubular fluid.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Acetates,
http://linkedlifedata.com/resource/pubmed/chemical/Acetazolamide,
http://linkedlifedata.com/resource/pubmed/chemical/Ammonia,
http://linkedlifedata.com/resource/pubmed/chemical/Buffers,
http://linkedlifedata.com/resource/pubmed/chemical/Culture Media
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0378-0392
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
179-91
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7169984-Acetates,
pubmed-meshheading:7169984-Acetazolamide,
pubmed-meshheading:7169984-Acidosis,
pubmed-meshheading:7169984-Ammonia,
pubmed-meshheading:7169984-Animals,
pubmed-meshheading:7169984-Buffers,
pubmed-meshheading:7169984-Culture Media,
pubmed-meshheading:7169984-Hydrogen-Ion Concentration,
pubmed-meshheading:7169984-Kidney Cortex,
pubmed-meshheading:7169984-Male,
pubmed-meshheading:7169984-Rabbits,
pubmed-meshheading:7169984-Rats,
pubmed-meshheading:7169984-Rats, Inbred Strains
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pubmed:year |
1982
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pubmed:articleTitle |
Alkalinization of the incubation medium by rat and rabbit renal cortical slices.
|
pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, U.S. Gov't, Non-P.H.S.
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