Linked Life Data

7144269

Source:http://linkedlifedata.com/resource/pubmed/id/7144269

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1983-1-19
pubmed:abstractText
Dogs with chronic bile duct ligation have a decreased natriuretic response ot an acute extracellular volume expansion. The present investigation was undertaken in order to study the role of hemodynamic factors in causing the decreased natriuretic response to extracellular volume expansion in chronic bile duct ligated dogs. Five trained, conscious dogs were studied before, and 6 weeks after chronic bile duct ligation, each dog serving as its own control. Under basal conditions systemic hemodynamics were normal following chronic bile duct ligation. However, chronic bile duct ligation was associated with a blunted pressor response to extracellular volume expansion. Thus, at peak extracellular volume expansion, chronic bile duct ligated dogs had smaller increase in mean arterial pressure (P less than 0.05), an exaggerated decrease in systemic vascular resistance (P less than 0.05), and similar cardiac output as compared with normal dogs. This blunted pressor response to extracellular volume expansion may contribute to the decreased natriuresis seen following this maneuver in chronic bile duct ligated dogs.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0302-2137
pubmed:author
pubmed:issnType
Print
pubmed:volume
60
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
217-20
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Blunted pressor response to volume load in conscious dogs with chronic bile duct ligation.
pubmed:publicationType
Journal Article