Linked Life Data

7133805

Source:http://linkedlifedata.com/resource/pubmed/id/7133805

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1982-12-16
pubmed:abstractText
The right ventricular (RV) and left ventricular (LV) free wall weights, ornithine decarboxylase (ODC) specific activity and polyamine content were determined in fetal, 1-, 2-, 7-, 14-, and 21-day-old rabbit hearts. There was a significant increase in the LV free wall weight and a decrease in RV free wall weight between 1-7 days. By day 7 the LV/RV mass ratio doubled and reached a ratio comparable to that seen in adult rabbit hearts. The rate of change in the LV and RV free wall weights were comparable after day 7. There was a significant increase in LV ODC specific activity and a decrease in RV ODC specific activity after birth. The LV ODC specific activity was significantly greater than RV ODC specific activity in both 1 and 2 day old rabbit hearts whereas they were not significantly different in 7 and 14 day old rabbit hearts. The molar content (nmoles/mg wet weight or nmoles/mg protein) of putrescine decreased approximately 3-fold after birth in the RV but increased approximately 2-fold in the LV. The molar content of spermidine and spermine was transiently increased after birth (1 day old) in both RV and LV with approximately a 2-fold increase in spermidine and a 2.5-fold (LV) and 4-fold (RV) increase in spermine content. The increase in LV putrescine content after birth was due, at least in part, to the observed increase in ODC specific activity in the LV free wall. The putrescine/spermidine ratio increased in the LV and decreased in the RV immediately after birth up to day 7. As opposed to the short-lived increase in spermidine and spermine observed in both the RV and the LV free wall, increased ODC specific activity and putrescine accumulation uniquely characterized the preferential growth of the LV between day 1 and 7.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0031-3998
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
721-7
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Polyamine metabolism during the perinatal development of the rabbit right and left ventricle.
pubmed:publicationType
Journal Article