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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-2
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pubmed:dateCreated |
1977-11-25
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pubmed:abstractText |
The two components of soluble antigen--antibody complexes, at the antigen excess, exhibit an increase in their binding ability to glass-fiber filters. This is demonstrated in two systems. In the 125I-BSA--anti-BSA system the proportion of 125I-BSA bound to the filter is markedly increased in the presence of anti-BSA antibodies. More than 80% of the antibody bound BSA can be removed by passage through the filter. In the other system, mouse gamma globulin (MGG)--125I-anti-MGG, the proportion of antibody bound to the filter increases with the increase in antigen concentration, whilst the presence of another, non-related, gamma globulin has little effect on the binding. The possible mechanisms for the binding of soluble complexes to the glass fibers are suggested and discussed.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0022-1759
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
21-9
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:71331-Animals,
pubmed-meshheading:71331-Antigen-Antibody Complex,
pubmed-meshheading:71331-Binding Sites, Antibody,
pubmed-meshheading:71331-Filtration,
pubmed-meshheading:71331-Glass,
pubmed-meshheading:71331-Humans,
pubmed-meshheading:71331-Iodine Radioisotopes,
pubmed-meshheading:71331-Mice,
pubmed-meshheading:71331-Rabbits,
pubmed-meshheading:71331-Serum Albumin, Bovine,
pubmed-meshheading:71331-Solubility,
pubmed-meshheading:71331-gamma-Globulins
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pubmed:year |
1977
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pubmed:articleTitle |
Interaction between soluble immune complexes and glass-fiber filters.
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pubmed:publicationType |
Journal Article
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