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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1982-12-16
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pubmed:abstractText |
The effect of aspirin n vitro and in vivo on platelet aggregation has been studied in 13 diabetic subjects without retinopathy, 16 diabetic subjects with retinopathy and 20 age- and sex-matched control subjects. The rate, degree and duration of collagen-induced aggregation were greater in the diabetic patients (p less than 0.05; p less than 0.01; p less than 0.05). The residual aggregation in vivo was greater in all diabetic patients with aspirin, whilst it only occurred in vitro in patients without retinopathy. A decreased latent period was seen in diabetic patients, to a greater extent in those with retinopathy. Significant differences in the rate, degree and duration of arachidonic acid-induced-aggregation were also seen in patients with retinopathy treated with aspirin (p less than 0.05; p less than 0.01; p less than 0.05). Disaggregation only occurred with aspirin in vitro and was more frequently seen in normal subjects.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0012-186X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
104-7
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:7128964-Arachidonic Acids,
pubmed-meshheading:7128964-Aspirin,
pubmed-meshheading:7128964-Collagen,
pubmed-meshheading:7128964-Diabetes Mellitus,
pubmed-meshheading:7128964-Diabetic Retinopathy,
pubmed-meshheading:7128964-Humans,
pubmed-meshheading:7128964-Middle Aged,
pubmed-meshheading:7128964-Platelet Aggregation
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pubmed:year |
1982
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pubmed:articleTitle |
Effect of aspirin on platelet aggregation in diabetes mellitus.
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pubmed:publicationType |
Journal Article
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